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APNG Optimizer is a small, simple application specially designed to help you optimize your PNG or APNG files with just a click. The compression algorithm this software uses is based on APNG Assembler and offers some interesting optimization tools like saving only a portion of the frame that has changed, palette sorting or colortype conversion.

So, if you need to optimize your APNG files, give this tool a try and check out if its capabilities can satisfy your needs.