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Thunderbird, Portable is the popular Mozilla Thunderbird email client bundled with a PortableApps.com launcher as a portable app, so you can take your email, address book and account settings with you. You can also add in GPG and Enigmail to encrypt and sign your email.

Thunderbird is a great email client from the same people who brought you the Firefox browser. Thunderbird gives you IMAP/POP support, a built-in RSS reader, support for HTML mail, powerful quick search, saved search folders, advanced message filtering, message grouping, labels, return receipts, smart address book LDAP address completion, import tools, and the ability to manage multiple e-mail and newsgroup accounts.

Features:

Mozilla Thunderbird is the safe, fast email client that's easy to use. It has lots of great features including quick message search, customizable views, support for IMAP/POP, RSS support and more. Plus, the portable version leaves no personal information behind on the machine you run it on, so you can take your email and adress book with you wherever you go.